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This is the study that matters most for the "before and after" question, because it used the exact demographic most GHK-Cu consumers belong to: women over 50 with real photodamage, not 25-year-olds with minor texture concerns

TB-500 stands out in systemic wound healing and muscle and cardiac regeneration, and as the only one of the two peptides with published human Phase 2 data

[2,9] This connection between gut-derived peptides and neurological function is an active area of investigation

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Adding cagrilintide to tirzepatide Theoretical protocol (not clinically studied): If on tirzepatide 10-15mg: Stable on tirzepatide for 4+ weeks Continue tirzepatide at current dose Add cagrilintide 0.6mg weekly Standard cagrilintide titration to 2.4mg Rationale: Tirzepatide is dual GIP/GLP-1 (very powerful alone) Adding amylin pathway could theoretically enhance No clinical data on this combination Uncertain if additional benefit over tirzepatide alone Concerns: GI side effects may be severe (both slow gastric emptying) Tirzepatide already produces 15-22% weight loss alone Unclear if cagrilintide adds meaningful benefit Expensive combination Verdict: Wait for clinical data